Cold and Flu Formula

Andrographis

This herb stimulates the immune system and studies have found that it reduces the severity of common cold symptoms such as sore throat, upper respiratory catarrh (phlegm), bronchial cough, and fever.

Andrographis contains the active constituent andrographolide (a diterpene lactone). Several double-blind clinical trials have found that Andrographis reduces the severity of mild URTI symptoms, such as a sore throat.

Caceres DD, Hancke JL, Burgos RA, et al. Use of visual analogue scale measurements (VAS) to assess the effectiveness of standardizedAndrographis paniculataextract SHA-10 in reducing the symptoms of common cold: a randomized double blind-placebo study. Phytomedicine 1999;6(4):217-223. Mills S, Bone K. Principles and practice of phytotherapy. Edinburgh: Churchill Livingstone, 2000. Coon JT, Ernst E.Andrographis paniculatain the treatment of upper respiratory tract infections: a systematic review of safety and efficacy. Planta Med 2004;70(4):293-298.

Preliminary evidence suggests that andrographis may increase antibody activity and phagocytosis by macrophages, contributing to its immunostimulatory properties.

Andrographis; Echinacea; Olive; Vitamin C; Zinc. Natural Medicines Comprehensive Database 2014. Viewed 14 March 2020, www.naturaldatabase.com

Echinacea

Many of us have heard the name echinacea but may not be sure why it’s so popular; it has antimicrobial and antiviral activity and has been traditionally used to support immune function and provide relief of upper respiratory catarrh, sore throat, and feverish conditions.

Mills S, Bone K. Principles and practice of phytotherapy. Edinburgh: Churchill Livingstone, 2000. Braun L, Cohen M. Herbs and natural supplements: an evidence-based guide, 2nd ed. Sydney: Churchill Livingstone Elsevier, 2007.

Echinacea supports the immune system through the non-specific cellular and humoral immune response,9 also increasing macrophage proliferation and phagocytosis.

Echinacea affects specific immunity by increasing the levels and activity of T-lymphocytes, neutrophils and natural killer cells.

Andrographis; Echinacea; Olive; Vitamin C; Zinc. Natural Medicines Comprehensive Database 2014. Viewed 14 March 2020, www.naturaldatabase.com

Olive leaf

Olive leaf has shown to possess antibacterial activity and is used in traditional western herbal medicine for respiratory ailments such as cough and sore throat.

Braun L, Cohen M. Herbs and natural supplements: an evidence-based guide, 2nd ed. Sydney: Churchill Livingstone Elsevier, 2007. Roxas M, Jurenka J. Coldsand influenza: areview of diagnosis and conventional, botanical, andnutritionalconsiderations. AlternMedRev2007;12(1):25-48. Bone K. A clinical guide to blending liquid herbs. St Louis: Churchill Livingstone, 2003.

Olive leaf has shown antiviral activity in early research.

Andrographis; Echinacea; Olive; Vitamin C; Zinc. Natural Medicines Comprehensive Database 2014. Viewed 21 January 2019, www.naturaldatabase.com

Zinc

Zinc is a well-known immune-support nutrient required for the production of white blood cells that fight infections; its deficiency is linked to decreased immune function.

Prasad AS. Zinc: role in immunity, oxidative stress, and chronic inflammation. Curr Opin Clin Nutr Metab Care 2009;12(6):646-652. Shils ME, Shike M, Ross AC, et al (Eds). Modern nutrition in health and disease, 10th ed. Philadelphia: Lippincott Williams & Wilkins, 2006. Marone G, Findlay SR, Lichtenstein LM. Modulation of histamine release from human basophils in vitro by physiological concentrations of zinc. J Pharmacol Exp Ther 1981;217(2):292-298.

Zinc is a structural component of a wide variety of proteins, cell membranes, neuropeptides, and hormone receptors. It supports the functioning of the healthy immune system by inhibiting the release of histamine from basophils and is necessary for the healthy production of lymphocytes.

Shils ME, Shike M, Ross AC, et al (Eds). Modern nutrition in health and disease, 10th ed. Philadelphia: Lippincott Williams & Wilkins, 2006. Marone G, Findlay SR, Lichtenstein LM. Modulation of histamine release from human basophils in vitro by physiological concentrations of zinc. J Pharmacol Exp Ther 1981;217(2):292-298.

Vitamin A

Betacarotene is a precursor for vitamin A, which plays an essential role in regulating the immune system and helps the body fight off infections. It also boosts the activity of white blood cells, which defend the body from foreign substances.

Wintergerst ES, Maggini S, Hornig DH. Contribution of selected vitamins and trace elements to immune function. Ann Nutr Metab 2007;51(4):301-323

Vitamin D

Vitamin D can modulate the innate and adaptive immune responses to bacteria and viruses. Deficiency in vitamin D is associated with increased autoimmunity as well as an increased susceptibility to infection.

Aranow C. Vitamin D and the immune system. Journal of investigative medicine: the official publication of the American Federation for Clinical Research. 2011; 59(6):881-6.

Contains Microcrystalline Cellulose as base

• Always follow directions for use, if you have any questions please contact us
• If symptoms persist, change or worsen talk to your health professional
• Supplements may only be of assistance if dietary intake is inadequate
• This product is not intended to diagnose, treat, cure, or prevent any disease, always talk to your health professional if you suspect you may have an undiagnosed medical condition
• Not recommended for use in children unless otherwise advised by a health professional
• This formula contains vitamin A (also called retinol, retinoids, or retinoic acid).
• The recommended daily amount of vitamin A from all sources is 700 micrograms retinol equivalents for women and 900 micrograms retinol equivalents for men
• WARNING – Contains zinc, which may be dangerous when used in large amounts or for a long period
• Large doses of Andrographis may cause gastric discomfort, vomiting or loss of appetite
• In rare cases, this product may be associated with taste disturbance

ALLERGY

• This product should not be used if you have a history of hypersensitivity to any of its ingredients
• WARNING – Andrographis and Echinacea may cause allergic reactions; if you have a severe reaction, stop use and seek immediate medical attention

PREGNANCY & BREASTFEEDING

• WARNING – When taken in excess of 3000 micrograms retinol equivalents, vitamin A can cause birth defects; if you are pregnant, or considering becoming pregnant, do not take vitamin A supplements without consulting your doctor or pharmacist

INTERACTIONS

• Do not use this product with other medicines, supplements, or topical products that contain vitamin A or are related to vitamin A unless otherwise directed by a health professional. This includes products containing isotretinoin (e.g. Roaccutane®, Oratane®, Dermatane™), tretinoin (e.g. ReTrieve®, Stieva-A™, Acnatac®), vitamin A, retinol, retinoids or retinoic acid. If you are unsure if a product contains vitamin A or works similarly to vitamin A, ask your doctor or pharmacist.
• This supplement may interact with anticoagulant or antiplatelet medications (increase risk of bleeding), immunosuppressive medications (opposing effects), antidiabetic or antihypertensive medications (additive effect) and certain antibiotics
• This supplement should not be used if you have bile stones
• If you have any pre-existing conditions, or are on any medications (including supplements, herbal or over-the-counter) always talk to your health professional before use
• Some supplements may need to be stopped for a certain period before elective surgery or medical tests, please confirm with your health professional

Supporting healthy immune function: Take ONE capsule ONCE daily for a maximum of TWO months continuously

When experiencing cold and flu symptoms: Take ONE capsule TWICE a day for the duration of the cold, for a maximum of TWO weeks

If you experience stomach discomfort when taking this supplement, take immediately after food

Store all medicines and products out of reach of children or pets.

Always check the expiry date on the label and do not use past the expiry date.

Keep in a cool dry place where the temperature stays below 25°C. Avoid direct sunlight and heat. Do not store this product, or any medicines in the bathroom or near a sink.